What happens to the molecular areal makeup of the whole cortex when you lose sensory inputs?  Great collaboration with Xiaoyin Chen (Allen Institute), Jesse Gillis (Toronto), Stephan Fisher (Inst. Pasteur) and Tony Zador (CSHL) using modern tools addresses this old question in unprecedented detail.  Using a high-throughput in situ sequencing technique (BARseq) over the whole cortex we show that binocular enucleation caused a shift of the cell-type compositional profiles of visual areas towards neighbouring cortical areas within the same module, suggesting that peripheral inputs sharpen the distinct transcriptomic identities of areas within cortical modules.  Read the paper in Nature. AIB news release