This was a long lift to get everything right. Hijee and Travis perfected in vivo holographic neuronal stimulation to stimulate small groups of individual auditory cortex neurons in vivo and test how this affects sound evoked responses. They shows that auditory cortex neurons with shared functional properties rapidly adjust their responses during sensory processing, revealing a circuit-level mechanism that regulates overall network activity balance. Read the paper here in eLife.

We showed a long time ago that the frequency organization of the auditory cortex on the single cell level is pretty messy. But does it mean that all functional connections are random or unorganized? Peter did careful 2-photon imaging and in collaboration with Sahar and Anuthhara from the Babadi lab shows that even though the frequency preference of neighboring neurons in A1 is functionally diverse, the functional connection patterns are functionally precise and harmonically related. Read more here: www.pnas.org/doi/10.1073/…